Free Energy Transduction and Biochemical Cycle Kinetics pdf

Terrell Leslie Hill (1917 - 2014) était un éminent physicien théoricien américain, physico-chimiste et biologiste moléculaire, qui était un scientifique de premier plan dans de nombreux domaines, principalement en mécanique statistique, mécanique quantique, physique chimique, physique de la matière condensée, biologie moléculaire théorique. et biochimie.

Free Energy Transduction and Biochemical Cycle Kinetics pdf par Terrell Hill

This small book is a simplified, abbreviated, and updated version of the author's Free Energy Transduction in Biology, published in 1977 (Academic Press, New York). The present book is meant to be a textbook for a class or for self-study. The first chapter gives a self-contained and elementary discussion of the principles of free energy transduction in biology. Section 5 includes new material on the Onsager coefficients Lij (for systems near equilibrium) not avail­ able in 1977. Some readers may wish to study the first chapter only. The second chapteris a little more sophisticated, and deals with the so-called diagram method for calculating steady-state probabili­ ties and cycle fluxes. Although these concepts are useful in the analysis of free energy transduction systems, they have an intrinsic importance and interest. Section 8 summarizes quite recent new results not included in the 1977 book. The third chapter is again a step more sophisticated. Some readers may wish to omit it. Free energy levels of the states in a kinetic diagram are introduced. This topic is primarily of conceptual inter­ est for ordinary kinetic diagrams but it is essential in understanding muscle contraction (and related systems) at the molecular level.