Introduction to bioinformatics pdf

亚瑟·马利·莱斯克 是一名蛋白质科学研究人员，他是位于大学公园的宾夕法尼亚州立大学的生物化学和分子生物学教授。 Lesk 于 1961 年以优异成绩获得哈佛大学学士学位。1966 年获得普林斯顿大学博士学位。他还于 1999 年获得英国剑桥大学硕士学位。Lesk 做出了重大贡献 用于蛋白质进化的研究。 他和在英国剑桥医学研究委员会（英国）分子生物学实验室工作的 Cyrus Chothia 通过分析蛋白质家族的进化机制，发现了氨基酸序列变化与蛋白质结构变化之间的关系。 发现为最成功和广泛使用的结构预测方法（称为同源建模）提供了定量基础。

Introduction to bioinformatics pdf 亚瑟·马利·莱斯克

Introduction to Bioinformatics by Arthur Lesk is a timely and much-needed textbook which provides an accessible and thorough introduction to a subject which is becoming a fundamental part of biological science today. As a pioneer of the use of bioinformatics techniques in research, Dr Lesk brings unrivalled experience and expertise to the study of this field. The aim of the book is to generate an understanding of the biological background of bioinformatics, and to integrate this with an introduction to the use of computational skills. Without describing computer science or sophisticated programming skills in detail, the book supports and encourages the application of the many powerful computational tools of bioinformatics in a way that is both relevant to and stimulating for the reader.
The book contains numerous problems and innovative Weblems (for Web-based Problems) to encourage students to engage with the subject and with the accompanying web site and to develop a working understanding and appreciation of the power of bioinformatics as a research tool.