Tissue and Organ Regeneration: Advances in Micro- and Nanotechnology pdf

Lijie Grace Zhang 教授的纳米医学和组织工程生物工程实验室在 3D/4D 生物打印、纳米技术、组织工程和药物递送方面应用了一系列跨学科技术和方法，用于各种生物医学应用。 正在进行的主要研究项目包括：开发先进的 3D/4D 生物打印技术和设计受生物学启发的纳米结构支架，用于复杂的心血管、神经和肌肉骨骼组织再生； 研究纳米和化学环境在指导干细胞分化用于再生医学方面的影响； 开发在疾病或癌症部位长期和受控药物释放的持续药物制剂； 开发用于癌症转移研究的新型 3D 可调组织模型； 和用于生物医学应用的 4D 打印软生物机器人。

Tissue and Organ Regeneration: Advances in Micro- and Nanotechnology pdf l I节优雅张

Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell–based techniques is that current therapies lack controlled environments that are crucial for regulating stem cell engraftment and differentiation in vivo, because stem cells are rather sensitive to even minute changes in their environment. Micro- and nanotechnology hold great potential to fabricate biomimetic spatiotemporally controlled scaffolds as well as control stem cell behavior and fate by micro- and nanoscale cues. This book presents the latest micro- and nanotechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. Moreover, it covers and details cutting-edge research in nano- and microfabrication techniques and biomaterials for the regeneration of various tissues and organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, cardiac, and vascular tissues.